Mistle is a glowing plant found in the world. You can interact with it and select to rest near it. When you rest, your HP and regeneration uses are restored along with your Ichor. However, your Ichor stock limit will return to normal if it has been increased by Gifts.
At a Mistle, you may also acquire Gifts contained in your Blood Codes by selecting "Acquire/Inherit Gifts", and increase your Gift proficiency using items.
All defeated enemies will revive after you rest.
You can also use the mistles to teleport to places you've visited before, after activating them.
Once they are, it allows other Revenants and humans to enter the areas you have already explored. By returning to said places, you might encounter someone new.
History[]
We learn a few details behind the history of mistle’s existence in the world of Vein through the Protagonist's Vestige found in the Cathedral of the Sacred Blood. In the Protagonist’s memory they come across a mistle when on mission as Jack Rutherford's partner. Jack instructs you in activating the mistle with a dark colored vial he hands to you.
Jack explains that the vial’s contents are a kind of medicine made from the Queen’s blood. This “medicine,” the masks for revenants, and other things were are part of the Queen’s plans before she became the Queen. It can be inferred from Jack’s dialogue that Cruz—the Queen—had made efforts to make life more livable for the revenants as they fought against the horrors through the plans Jack mentions. The Lost and the miasma they gave off would have been in existence when Cruz was undergoing experimentation under the QUEEN project.
It would make sense for Cruz to have created mistle with her powers to help clear the air of the bloodlust-inducing miasma. The medicine made from her blood and the revenant masks would have been part of the measures to help revenants in their efforts to fight without going into frenzy from the miasma.
(It is worth mentioning that while mistles and bloodsprings share a very similar appearance–like they are the same kind of plant—bloodsprings did not appear until after the Queen was defeated in Operation Queenslayer).